abstract：:The cytokines tumor necrosis factor-alpha (TNF-alpha), interleukin-8 (IL-8), and intercellular adhesion molecule-1 (ICAM-1) have important roles in regulating neutrophil migration and the inflammatory response. To determine whether the concentration of these cytokines and soluble ICAM-1 (sICAM-1) in sputum was increas...

journal_title：Pediatric pulmonology

authors： Salva PS,Doyle NA,Graham L,Eigen H,Doerschuk CM

更新日期：1996-01-01 00:00:00

abstract：:Respiratory inductive plethysmography (RIP) is a simple technique for an objective, noninvasive assessment of thoracoabdominal asynchrony, which in turn is an indirect measure of airway obstruction. We evaluated different indices of asynchrony obtained by RIP before and after methacholine-induced airway obstruction. B...

journal_title：Pediatric pulmonology

authors： Rusconi F,Gagliardi L,Aston H,Silverman M

更新日期：1995-12-01 00:00:00

abstract：:Pulmonary function and exercise tolerance were evaluated in late childhood in two groups of prematurely born children: one group with bronchopulmonary dysplasia (BPD) [n = 15; gestational age at birth (GA): 29.6 +/- 2.8 weeks; birth weight (BW): 1,367 +/- 548 g; age at test: 7.9 +/- 0.6 years], and a second group with...

journal_title：Pediatric pulmonology

authors： Parat S,Moriette G,Delaperche MF,Escourrou P,Denjean A,Gaultier C

更新日期：1995-11-01 00:00:00

abstract：:C-reactive protein (CRP) concentrations were evaluated in 9 cystic fibrosis (CF) patients with acute pulmonary exacerbations and 14 patients with acute exacerbations of asthma without any symptoms of an acute infection. CRP concentrations were serially evaluated over the course of therapy in CF patients and compared w...

journal_title：Pediatric pulmonology

authors： Friesen CA,Wiens LA,Burry VF,Portnoy J,Roberts CC

更新日期：1995-10-01 00:00:00

abstract：:It has been suggested that children with asthma recover more quickly from exercise-induced bronchoconstriction than adults. On the basis of clinical observation we hypothesized that recovery rate from exercise-induced asthma (EIA) in childhood also decreases with age. In 14 children (aged 7-12 years) with a history of...

journal_title：Pediatric pulmonology

authors： Hofstra WB,Sterk PJ,Neijens HJ,Kouwenberg JM,Duiverman EJ

更新日期：1995-09-01 00:00:00

abstract：:It has been previously shown that prophylactic, intravenous dexamethasone (DEX) and intratracheal recombinant human Cu/Zn superoxide dismutase (SOD) ameliorate lung injury in newborn piglets treated with 48 hr of hyperoxia and mechanical ventilation. DEX has many pharmacologic effects, including the possible induction...

journal_title：Pediatric pulmonology

authors： Davis JM,Robbins CG,Anderson T,Sahgal N,Genen L,Tierney J,Horowitz S

更新日期：1995-08-01 00:00:00

abstract：:The purpose of this study was to compare the pathogens obtained by oropharyngeal suction (OPS) and bronchoalveolar lavage (BAL) in children with chronic pulmonary infections. Forty-four children (mean age of 6.1 years; range 4 months to 15 years) were included in the study (27 children with recurrent localized lung in...

journal_title：Pediatric pulmonology

authors： Avital A,Uwyyed K,Picard E,Godfrey S,Springer C

更新日期：1995-07-01 00:00:00

abstract：:Bronchial responsiveness to isocapnic hyperventilation with cold air (CAH) and to inhaled methacholine (MCH) was compared in 17 children with bronchial asthma. The response to cold air was expressed as the percent drop in FEV1 from baseline at 4 min. after the challenge (delta % FEV1 CAH), and the response to methacho...

journal_title：Pediatric pulmonology

authors： de Benedictis FM,Canny GJ,MacLusky IB,Levison H

更新日期：1995-06-01 00:00:00

abstract：:Failure to recognize esophageal intubation can result in severe hypoxia and permanent neurologic injury. Capnography is a standard monitoring modality in the operating room but has not been utilized fully in other environments. We used capnography at the time of endotracheal intubation in the neonatal intensive care u...

journal_title：Pediatric pulmonology

authors： Roberts WA,Maniscalco WM,Cohen AR,Litman RS,Chhibber A

更新日期：1995-05-01 00:00:00

abstract：:Little attention has been focused on the progressive pulmonary deterioration which occurs in mechanically ventilated infants with normal or mildly abnormal lungs. We hypothesized that lung function would deteriorate over a 24-hr period in anesthetized neonatal piglets with normal lungs mechanically ventilated at 2 cm ...

journal_title：Pediatric pulmonology

authors： Easa D,Finn KC,Balaraman V,Sood S,Wilkerson S,Takenaka W,Mundie TG

更新日期：1995-03-01 00:00:00

abstract：:The effects of current methods of bone marrow transplantation (BMT) on pulmonary function in children have not been extensively studied. We reviewed serial pulmonary function tests (PFTs) in 25 children (median age, 9 yr; range, 4-15) who received allogeneic (n = 14) or autologous (n = 11) BMT for neoplastic diseases ...

journal_title：Pediatric pulmonology

authors： Quigley PM,Yeager AM,Loughlin GM

更新日期：1994-12-01 00:00:00

abstract：:We assessed the ability of innovative lung function tests to detect bronchial obstruction induced by methacholine bronchial challenge. Fifty-five recurrently wheezy infants (mean age 16 +/- 5.2 months) free of respiratory symptoms underwent baseline lung function tests. Forty-two completed the methacholine challenge. ...

journal_title：Pediatric pulmonology

authors： Benoist MR,Brouard JJ,Rufin P,Delacourt C,Waernessyckle S,Scheinmann P

更新日期：1994-11-01 00:00:00

abstract：:Home mattresses of 24 asthmatic children with house dust mite allergy were sprayed with either benzyl-benzoate foam or placebo in a double blind fashion, 10 days before the children left the residential house for asthmatic children Istituto Pio XII (located in the Italian Alps in an environment free of mites) and went...

journal_title：Pediatric pulmonology

authors： Sette L,Comis A,Marcucci F,Sensi L,Piacentini GL,Boner AL

更新日期：1994-10-01 00:00:00

abstract：:There is no consensus about reproducibility and reliability of spirometry in young children. We evaluated forced expiratory maneuvers from 98 children aged 3 to 5 years with a variety of respiratory disorders before and after bronchodilator treatment. Forced vital capacity (FVC) and forced expiratory volume in 1 sec (...

journal_title：Pediatric pulmonology

authors： Kanengiser S,Dozor AJ

更新日期：1994-09-01 00:00:00

abstract：:We report the case of a 4-year-old child with an atypical presentation of an aspirated unwitnessed foreign body in the airway. During an attempt to obtain a biopsy of what appeared to be a mucosal growth, the foreign body was removed. This may be the first report of foreign body removal in a child this young, using a ...

journal_title：Pediatric pulmonology

authors： Akhter J,Gaspar M,Bassuk A,Roberts J

更新日期：1994-07-01 00:00:00

abstract：:Two male patients with cystic fibrosis (CF), both 18 years old, developed frontal lobe brain abscesses. Both patients presented with histories of intermittent headache over several days and occasional vomiting. Headache was not more evident in the mornings and not associated with visual disturbance in either patient. ...

journal_title：Pediatric pulmonology

authors： Cooper DM,Russell LE,Henry RL

更新日期：1994-06-01 00:00:00

abstract：:Nine young asthmatic children aged 2-5 years underwent methacholine challenge after placebo or albuterol administered by metered dose inhaler through a spacer device (Babyhaler) with a face mask in a double-blind, cross-over, randomized study. The methacholine challenge was performed using chest auscultation to define...

journal_title：Pediatric pulmonology

authors： Avital A,Godfrey S,Schachter J,Springer C

更新日期：1994-05-01 00:00:00

abstract：:The purpose of this study was to determine if the interrupter technique, a noninvasive method for measuring airflow resistance, could be used to assess airway obstruction in children. In 107 children (74 with asthma, 12 with cystic fibrosis, and 21 without lung disease) conductance (mostly of airways) measured with th...

journal_title：Pediatric pulmonology

authors： Carter ER,Stecenko AA,Pollock BH,Jaeger MJ

更新日期：1994-04-01 00:00:00

abstract：:End-tidal PCO2 (PETCO2) measurements from two commercially available neonatal infrared capnometers with different sampling systems and a mass spectrometer were compared with arterial PCO2 (PaCO2) to determine whether the former could predict the latter in mechanically ventilated rabbits with and without lung injury. T...

journal_title：Pediatric pulmonology

authors： Hopper AO,Nystrom GA,Deming DD,Brown WR,Peabody JL

更新日期：1994-03-01 00:00:00

abstract：:Allergic bronchopulmonary aspergillosis (ABPA) is a well-known complication of cystic fibrosis (CF), with an estimated incidence of up to 11%. In patients with CF, the diagnosis of ABPA must be based on significant elevation of Aspergillus fumigatus (Af) antibody and total serum IgE, since it is common to already have...

journal_title：Pediatric pulmonology

authors： Chung Y,Kraut JR,Stone AM,Valaitis J

更新日期：1994-02-01 00:00:00

abstract：:The optimal duration of therapy for acute exacerbations of cystic fibrosis (CF) has not been defined, and the utility of serial pulmonary function testing in predicting the duration of therapy has yet to be established. In a review of 90 pulmonary exacerbations of 39 patients with CF requiring hospitalization, we foun...

journal_title：Pediatric pulmonology

authors： Rosenberg SM,Schramm CM

更新日期：1993-10-01 00:00:00

abstract：:Ten infants with evidence of impending respiratory failure from severe bronchiolitis were successfully treated with continuous positive airway pressure (NCPAP) with double nasal prongs. Their mean (SD) age was 6.7 (3.8) months and mean (SD) body weight was 7.1 (2.1) kg. Respiratory assessments were made immediately be...

journal_title：Pediatric pulmonology

authors： Soong WJ,Hwang B,Tang RB

更新日期：1993-09-01 00:00:00

abstract：:The clinical course of sarcoidosis in children has not been well defined. Eight children with symptomatic sarcoidosis included in this study underwent pulmonary function tests and bronchoscopy with bronchoalveolar lavage (BAL) before treatment and during steroid therapy. At the start of therapy, functional parameters,...

journal_title：Pediatric pulmonology

authors： Chadelat K,Baculard A,Grimfeld A,Tournier G,Boule M,Boccon-Gibod L,Clement A

更新日期：1993-07-01 00:00:00

abstract：:Our study was aimed at elucidating the effect of strenuous maternal exercise (running at a speed of 20 m/min) on fetal somatic growth and lung development. Dams were separated into three groups: (1) exercising during the entire course of pregnancy; (2) exercising from the 16th to the 20th gestational day; and (3) cont...

journal_title：Pediatric pulmonology

authors： Nagai A,Sakamoto K,Konno K

更新日期：1993-06-01 00:00:00

abstract：:The airway occlusion techniques for assessing passive respiratory mechanics have become well established methods in fullterm neonates and older infants. The single breath technique (SBT) is frequently used for assessing lung function in intubated infants on neonatal intensive care units. However, less is known about t...

journal_title：Pediatric pulmonology

authors： Gappa M,Rabbette PS,Costeloe KL,Stocks J

更新日期：1993-05-01 00:00:00

abstract：:Bronchial reactivity was assessed in 66 children with bronchial asthma (aged 8-15 years) by provocation with histamine-HCl during a symptom-free period. A significant bronchial reaction to histamine was defined as a 50% increase in the resistance of the respiratory system (Rrs) determined by the forced oscillation tec...

journal_title：Pediatric pulmonology

authors： Holmgren D,Engström I,Bjure J,Sixt R,Aberg N

更新日期：1993-03-01 00:00:00

abstract：:Measurements of thoracic gas volume (TGV), airway resistance (Raw), and airway conductance (Gaw) were calculated in a group of 42 normal infants using a whole-body plethysmograph. Maximum expiratory flow at functional residual capacity was measured in a separate group of 108 normal infants. Using data obtained from th...

journal_title：Pediatric pulmonology

authors： Hampton F,Beardsmore CS,Morgan W,Williams A,Taussig L,Thompson JR

更新日期：1992-11-01 00:00:00

abstract：:Four patients with generalized lymphangiomatosis presenting with chylothoraces are described. All four had bone involvement, two had involvement of the spleen, and one of the pericardium. The diagnosis was confirmed by typical radiology, histology, and in three patients by immunohistochemistry. Treatment was mainly pa...

journal_title：Pediatric pulmonology

authors： Shah AR,Dinwiddie R,Woolf D,Ramani R,Higgins JN,Matthew DJ

更新日期：1992-10-01 00:00:00

abstract：:We have studied the effect of triamcinolone acetonide (TAC) on airway morphogenesis of the Sprague-Dawley fetal rat in whole organ lung cultures from day 15 to day 21 of equivalent gestational age (6 days in culture). TAC produced an increased number of peripheral buds from day 18 onward and the airway and airspaces h...

journal_title：Pediatric pulmonology

authors： Massoud EA,Sekhon HS,Rotschild A,Thurlbeck WM

更新日期：1992-09-01 00:00:00

abstract：:Severe bronchopulmonary dysplasia (BPD) is frequently associated with asthma. The combination is often severe enough to necessitate corticosteroid therapy. There are no commercially available nebulizer solutions of corticosteroids for use in infants and young children. Seven infants and small children with very severe...

journal_title：Pediatric pulmonology

authors： König P,Shatley M,Levine C,Mawhinney TP

更新日期：1992-08-01 00:00:00

abstract：:A potentially useful method to monitor respiratory mechanics in artificially ventilated patients consists of analyzing the relationship between tracheal pressure (P), lung volume (V), and gas flow (V) by multiple linear regression (MLR) using a suitable model. Contrary to other methods, it does not require any particu...

journal_title：Pediatric pulmonology

authors： Rousselot JM,Peslin R,Duvivier C

更新日期：1992-07-01 00:00:00

abstract：:Fine needle aspiration biopsy cytology performed in three children with sarcoidosis expedited clinical investigation and diagnosis of their disease. Each patient had a different clinical presentation; in two of them lymphoma was part of the initial differential diagnosis. Aspiration cytology in all cases revealed coll...

journal_title：Pediatric pulmonology

authors： Wakely PE Jr,Silverman JF,Holbrook CT,Fairman RP,Daeschner CW 3rd,Joshi VV

更新日期：1992-06-01 00:00:00

abstract：:The aim of the study was to evaluate the effects of inhaled steroids (IS) on the improvement of clinical asthma symptoms and on the decrease in bronchial hyperreactivity (BHR). Twenty-four children with severe asthma were given 1,000 micrograms beclomethasone dipropionate (BDP) daily and compared with ten asthmatic co...

journal_title：Pediatric pulmonology

authors： Benoist MR,Brouard JJ,Rufin P,Waernessyckle S,de Blic J,Paupe J,Scheinmann P

更新日期：1992-06-01 00:00:00

abstract：:Bronchoalveolar lavage (BAL) performed with a fiberoptic bronchoscope (FOB) is a useful method for sampling alveolar contents. Since the smallest FOB with a channel has a diameter of 3.6 mm, BAL is difficult to accomplish through artificial airways (AA) less than 5.0 mm I.D. We used a 4F balloon wedge pressure cathete...

journal_title：Pediatric pulmonology

authors： Alpert BE,O'Sullivan BP,Panitch HB

更新日期：1992-05-01 00:00:00

abstract：:Since July 1988, a total of 92 transbronchial biopsies (TBB) have been performed in 18 patients (aged 3-16 years). Twelve patients (67%) were heart-lung transplant (HLT) recipients undergoing surveillance for pulmonary graft rejection and infection. The remainder included immunocompromised patients at risk of opportun...

journal_title：Pediatric pulmonology

authors： Whitehead B,Scott JP,Helms P,Malone M,Macrae D,Higenbottam TW,Smyth RL,Wallwork J,Elliott M,de Leval M

更新日期：1992-04-01 00:00:00

abstract：:We examined the effects of within-breath changes in compliance (C) upon the accuracy of measurements of compliance and resistance (R) by linear regression analysis and by Mead and Wittenberger's method. These effects were illustrated by a computer model and by lung models with linear and nonlinear pressure/volume rela...

journal_title：Pediatric pulmonology

authors： Silva Neto G,Gerhardt T,Silberberg A,Gerhardt T,Claure N,Duara S,Bancalari E

更新日期：1992-03-01 00:00:00

abstract：:To determine the extent of pulmonary dysfunction following primary closure of an abdominal wall defect, we obtained pulmonary function tests (PFT) in 11 newborn infants with gastroschisis and 6 with large omphaloceles admitted to a newborn ICU in a children's hospital. Patients were 1 to 30 days of age at the time of ...

journal_title：Pediatric pulmonology

authors： Nakayama DK,Mutich R,Motoyama EK

更新日期：1992-03-01 00:00:00

abstract：:In contrast to its effect on airway smooth muscle in the adult, in vitro studies have shown that caffeine significantly increases active tension in airway smooth muscle in the neonatal lamb. To determine if caffeine has a physiological effect on airway function during early development, we studied the effect of caffei...

journal_title：Pediatric pulmonology

authors： Keklikian EN,Wolfson MR,Shaffer TH

更新日期：1992-01-01 00:00:00

abstract：:Previously, there was insufficient evidence to confirm that pneumonia in infants and children might lead to the development of pulmonary hypertension. Recently, it has been shown that acceleration time corrected for heart rate (ATc) and the ratios of right ventricular preejection period to right ventricular ejection t...

journal_title：Pediatric pulmonology

authors： Du JB,Li SZ,Wang BL,Li YA

更新日期：1991-01-01 00:00:00

abstract：:We retrospectively reviewed the spectrum, course, and outcome of pulmonary diseases in 66 children with AIDS, hospitalized between 1982 and 1988, prior to the use of zidovudine. Fifty-two of the 66 (79%) patients developed pulmonary problems. In fifty-two percent of all patients, a pulmonary problem was the first symp...

journal_title：Pediatric pulmonology

authors： Marolda J,Pace B,Bonforte RJ,Kotin NM,Rabinowitz J,Kattan M

更新日期：1991-01-01 00:00:00